Tools & Databases
A collection of bioinformatics platforms, machine-learning pipelines, and curated databases developed by the Integrative Biology Laboratory to accelerate reverse vaccinology, antimicrobial resistance surveillance, and pathogen genomics.
§1 Databases
3 resourcesCurated, searchable repositories of antimicrobial peptide and resistance-associated sequence data, built for reuse across the AMR research community.
AbAMPdb
A dedicated repository of antibacterial peptides curated for structural and functional annotation, supporting discovery of novel antimicrobial candidates against drug-resistant pathogens.
ESKAPE AMPdb
An antimicrobial peptide database focused specifically on the ESKAPE pathogen group, compiling sequence, structural, and activity data to guide peptide-based therapeutic design.
PAAMPdb
A curated database of antimicrobial peptides derived from Pseudomonas aeruginosa, providing sequence and activity information for research on this high-priority pathogen.
§2 Tools & Pipelines
6 platformsComputational pipelines spanning reverse vaccinology, pangenome analysis, and machine-learning-driven resistance profiling.
VacSol-ML (ESKAPE)
A machine-learning-enhanced reverse vaccinology pipeline that prioritizes vaccine target candidates specifically across ESKAPE pathogen proteomes.
B-vac
A bacterial vaccine target prediction platform that integrates subtractive genomics with reverse vaccinology to shortlist high-confidence antigen candidates.
B-Pan
An integrated pangenome analysis pipeline that characterizes genomic diversity through core/accessory genome identification, COG functional annotation, and phylogenetic reconstruction.
VacSol
The lab's original reverse vaccinology pipeline, automating subtractive proteomics to identify vaccine and drug target candidates from bacterial genomes.
PanRV
A pangenome-driven reverse vaccinology pipeline that combines core and accessory genome analysis to pinpoint conserved, immunogenic vaccine targets.
ResPred.AI
An AI-driven prediction engine that profiles antimicrobial resistance signatures directly from genomic data to support rapid surveillance and clinical decision-making.
§3 In Development
1 resourceCurrently under construction. Check back for release announcements.
B-vac.AI
A next-generation, machine-learning-based vaccine development tool built to accelerate target discovery across WHO-priority pathogens.
